Budapest Post

Cum Deo pro Patria et Libertate
Budapest, Europe and world news

What it does to the body

The coronavirus emerged in only December last year, but already the world is dealing with a pandemic of the virus and the disease it causes - Covid-19.

For most, the disease is mild, but some people die.

So how is the virus attacking the body, why are some people being killed and how is it treated?


Incubation period

This is when the virus is establishing itself.

Viruses work by getting inside the cells your body is made of and then hijacking them.

The coronavirus, officially called Sars-CoV-2, can invade your body when you breathe it in (after someone coughs nearby) or you touch a contaminated surface and then your face.

It first infects the cells lining your throat, airways and lungs and turns them into "coronavirus factories" that spew out huge numbers of new viruses that go on to infect yet more cells.

At this early stage, you will not be sick and some people may never develop symptoms.

The incubation period, the time between infection and first symptoms appearing, varies widely, but is five days on average.


Mild disease

This is all most people will experience.

Covid-19 is a mild infection for eight out of 10 people who get it and the core symptoms are a fever and a cough.

Body aches, sore throat and a headache are all possible, but not guaranteed.

The fever, and generally feeling grotty, is a result of your immune system responding to the infection. It has recognised the virus as a hostile invader and signals to the rest of the body something is wrong by releasing chemicals called cytokines.

These rally the immune system, but also cause the body aches, pain and fever.

The coronavirus cough is initially a dry one (you're not bringing stuff up) and this is probably down to irritation of cells as they become infected by the virus.

Some people will eventually start coughing up sputum - a thick mucus containing dead lung cells killed by the virus.

These symptoms are treated with bed rest, plenty of fluids and paracetamol. You won't need specialist hospital care.

This stage lasts about a week - at which point most recover because their immune system has fought off the virus.

However, some will develop a more serious form of Covid-19.

This is the best we understand at the moment about this stage, however, there are studies emerging that suggest the disease can cause more cold-like symptoms such as a runny nose too.


Severe disease

If the disease progresses it will be due to the immune system overreacting to the virus.

Those chemical signals to the rest of the body cause inflammation, but this needs to be delicately balanced. Too much inflammation can cause collateral damage throughout the body.

"The virus is triggering an imbalance in the immune response, there's too much inflammation, how it is doing this we don't know," said Dr Nathalie MacDermott, from King's College London.

Inflammation of the lungs is called pneumonia.

If it was possible to travel through your mouth down the windpipe and through the tiny tubes in your lungs, you'd eventually end up in tiny little air sacs.

This is where oxygen moves into the blood and carbon dioxide moves out, but in pneumonia the tiny sacs start to fill with water and can eventually cause shortness of breath and difficulty breathing.

Some people will need a ventilator to help them breathe.

This stage is thought to affect around 14% of people, based on data from China.


Critical disease

It is estimated around 6% of cases become critically ill.

By this point the body is starting to fail and there is a real chance of death.

The problem is the immune system is now spiralling out of control and causing damage throughout the body.

It can lead to septic shock when the blood pressure drops to dangerously low levels and organs stop working properly or fail completely.

Acute respiratory distress syndrome caused by widespread inflammation in the lungs stops the body getting enough oxygen it needs to survive. It can stop the kidneys from cleaning the blood and damage the lining of your intestines.

"The virus sets up such a huge degree of inflammation that you succumb... it becomes multi-organ failure," Dr Bharat Pankhania said.

And if the immune system cannot get on top of the virus, then it will eventually spread to every corner of the body where it can cause even more damage.

Treatment by this stage will be highly invasive and can include ECMO or extra-corporeal membrane oxygenation.

This is essentially an artificial lung that takes blood out of the body through thick tubes, oxygenates it and pumps it back in.

But eventually the damage can reach fatal levels at which organs can no longer keep the body alive.


The first deaths

Doctors have described how some patients died despite their best efforts.

The first two patients to die at Jinyintan Hospital in Wuhan, China, detailed in the Lancet Medical journal, were seemingly healthy, although they were long-term smokers and that would have weakened their lungs.

The first, a 61-year-old man, had severe pneumonia by the time he arrived at hospital.

He was in acute respiratory distress, and despite being put on a ventilator, his lungs failed and his heart stopped beating.

He died 11 days after he was admitted.

The second patient, a 69-year-old man, also had acute respiratory distress syndrome.

He was attached to an ECMO machine but this wasn't enough. He died of severe pneumonia and septic shock when his blood pressure collapsed.

AI Disclaimer: An advanced artificial intelligence (AI) system generated the content of this page on its own. This innovative technology conducts extensive research from a variety of reliable sources, performs rigorous fact-checking and verification, cleans up and balances biased or manipulated content, and presents a minimal factual summary that is just enough yet essential for you to function as an informed and educated citizen. Please keep in mind, however, that this system is an evolving technology, and as a result, the article may contain accidental inaccuracies or errors. We urge you to help us improve our site by reporting any inaccuracies you find using the "Contact Us" link at the bottom of this page. Your helpful feedback helps us improve our system and deliver more precise content. When you find an article of interest here, please look for the full and extensive coverage of this topic in traditional news sources, as they are written by professional journalists that we try to support, not replace. We appreciate your understanding and assistance.
Newsletter

Related Articles

0:00
0:00
Close
AI’s Next Bottleneck Is Power, Not Just Nvidia Chips
Meta Raises AI Spending Target to as Much as $145bn Despite Pressure Over Returns
Danube Drought Exposes Nazi Wrecks and Pushes Central Europe’s Power System to the Brink
Joe Biden’s Cancer Has Spread Beyond His Bones, Hunter Biden Says
Why 2027 Could Be a Strong Year for Stocks—and Why the Forecast Is Fragile
Why Markets May Look Quiet in August After Big Tech Earnings
UK Drought Cuts Harvests and Raises Food-Security Fears
UFO: Pentagon Releases Video of Unidentified Object Tracked Over Middle East
Ukraine Tells Senate Republicans Its Drone War Offers a Blueprint for America
Weight-Loss Drug Boom Tests the Limits of Prescription Advertising Rules
Senate Scrutinises AI-Driven Personalised Pricing
Spain Seeks Mainland Transfers for 1,100 Children Stranded in Ceuta
Spain and Morocco Trade Blame After 72,000 Migrants Enter Ceuta
AI Is Remaking the US Economy, From GDP Growth to iPhone Prices
Europe’s Heat and Drought Are Now Disrupting Power, Shipping and Tourism
Europe’s Drying Rivers Trigger Power Cuts, Factory Shutdowns and Wildfire Emergencies
Record-Low Danube Forces Nuclear Cuts and Emergency Power Curbs
Danube Drought Forces Hungary’s Paks Nuclear Plant Into Full Shutdown
Ceuta Death Toll Rises as Spain and Europe Clash Over Border Response
Valued at $109 Million: F-35B Fighter Jet Crashes in Southern California
Record-Low Danube Exposes Probable Mammoth Remains in Bulgaria
US Says It Has Carried Out Heavy Strikes on Iran After Attempted Attacks on Its Forces
The AI User Nightmare: Private Claude Conversations Leaked to the Internet
Over 24 Hours in the Air: Qantas Airbus Completes Record-Breaking Test Flight
Massive Wildfires Ravage Southern Europe: Fatalities in Greece and Evacuations Across France, Spain, and Turkey
Nvidia Reportedly Takes Vast Texas Data-Centre Lease to Underwrite AI Expansion
FIFA’s Private-Investment Plan for World Cup Rights Draws European Revolt
Apple Briefly Crosses Five Trillion Dollar Valuation as Investors Retreat From AI Bets
Fresh Heatwave Threatens to Rekindle France’s Historic Wildfire Crisis
Following OpenAI's Cyberattack: 'Most Companies Still Do Not Understand What Is Coming'
OpenAI Sued After ChatGPT Allegedly Discouraged Emergency Care Before Near-Fatal Embolism
Miliband Sets Climate and International Law at Centre of UK Diplomacy
Czech Central Bank Governor Rejects Early Euro Entry and Rate-Cut Pressure
Trump Readies New Tariffs as Temporary Global Levy Nears Expiry
Vivienne Westwood Casts Cicciolina, 74, in Its New Autumn Campaign
Dejavu: Germany’s Military Expansion Reshapes Europe’s Strategic Balance With France
Morgan Stanley Builds a Wall Street Lead in AI Infrastructure Finance
High Prices Push Coffee Drinkers Toward Whole Beans and Home Brewing
Trump Draws Boos and Podium Scrutiny at Spain’s World Cup Triumph
Brilliant move: Péter Magyar Moves to Nominate Chess Grandmaster Judit Polgár as Hungary’s President
Spain Defeats Argentina in Extra Time to Win Second World Cup
Current AI Seeks to Build an Open Global AI Infrastructure Outside Big Tech Control
Germany’s Economic Malaise Reopens the Sunday Shopping Debate
Proposed U.S.-Saudi Nuclear Pact Could Permit Limited Uranium Enrichment Under International Safeguards
Netherlands Declares Water Shortage Emergency After Drought Pushes Rivers to Historic Lows
Why Kentucky Fried Chicken Became KFC—and Why the False Explanations Persist
Ukrainian Drones Strike Wildberries Warehouses Deep Inside Russia
Reported CIA Mission Helped Clear the UAE’s Path to Advanced US AI Chips
Artificial Intelligence Capital Fuels Markets While Governments and Regulators Face Mounting Strategic Tests
China’s Moonshot’s Kimi K3 Narrows the Gap With Anthropic Through Scale, Openness and Lower Cost
×