Budapest Post

Cum Deo pro Patria et Libertate
Budapest, Europe and world news

Oxford, WHO scientists say more data needed on AstraZeneca's Covid vaccine trials

Oxford, WHO scientists say more data needed on AstraZeneca's Covid vaccine trials

More data is needed from AstraZeneca's Covid vaccine trials beyond what was presented in a press release, experts from the WHO and Oxford University said.

More data will be needed from AstraZeneca’s coronavirus vaccine trials to determine the drug’s safety and efficacy following concerns from experts in the U.S., scientists from the University of Oxford and the World Health Organizations said on Friday.

“There’s always a problem in announcing scientific results by press release, and that is that you don’t have all the data out there and people aren’t able to really look and think about the data properly,” Sir John Bell, the Regius professor of medicine at Oxford University, told CNBC’s “Closing Bell” on Friday.

Shares of AstraZeneca dipped this week after the company announced interim results from its coronavirus vaccine trials on Monday. The British pharmaceutical giant said its vaccine, which it’s developing alongside Oxford, was 70% effective after it combined results from two different dosing regimes.

One smaller group of people, all under the age of 55, received an unintentionally lower dose of the vaccine followed by a full dose, and a larger group of people received two full doses of the vaccine. The vaccine was found to be 90% effective in the group that received the smaller dose while the larger group showed only 62% effectiveness.

Some U.S. experts, including Moncef Slaoui, chief of the White House’s Operation Warp Speed, said they were concerned about the differing ages between the two groups. Amid those concerns, Pascal Soriot, CEO of AstraZeneca, told Bloomberg on Thursday that the company will likely begin a new study to examine the lower dosage regime.

“The full data will be published in the medical journal so people can examine it. Taking snippets of data is not a helpful way to make an analysis of what’s actually going on,” Bell told CNBC on Friday.

Other British government ministers and experts have also backed AstraZeneca’s vaccine, noting that drug regulators who have more information on the vaccine’s late-stage clinical trials will ultimately have the final say. Britain asked its medicine regulator on Friday to assess the vaccine for a temporary supply, which means the vaccine could be distributed in the country before the end of the year.


That process could take longer in the U.S., however, amid recent concerns. Bell told CNBC that he predicts the UK could be “substantially vaccinated” by spring of next year.

Kate O’Brien, director of immunization, vaccines and biologicals at WHO, agreed with Bell during the organization’s press briefing earlier on Friday, saying that there’s only a “limited amount that can be said in a press release” and that more information, including how well the vaccine builds an immune response, is needed.

“It’s difficult to weigh in on this,” O’Brien said from the WHO’s Geneva headquarters. “From what we understand about the press release, there is certainly something interesting that has been observed, but there are many reasons that could underlie the differences that were observed.”

Dr. Soumya Swaminathan, WHO’s chief scientist, concurred and said AstraZeneca’s trial figures “are still too small to really come to any definitive conclusions.” Less than 3,000 trial participants were in the group that was given the smaller dose of the company’s vaccine compared with more than 8,000 in the larger group.

“If we are to explore this hypothesis of having perhaps a better efficacy with the lower dose, then it would need a trial,” Swaminathan said.

AI Disclaimer: An advanced artificial intelligence (AI) system generated the content of this page on its own. This innovative technology conducts extensive research from a variety of reliable sources, performs rigorous fact-checking and verification, cleans up and balances biased or manipulated content, and presents a minimal factual summary that is just enough yet essential for you to function as an informed and educated citizen. Please keep in mind, however, that this system is an evolving technology, and as a result, the article may contain accidental inaccuracies or errors. We urge you to help us improve our site by reporting any inaccuracies you find using the "Contact Us" link at the bottom of this page. Your helpful feedback helps us improve our system and deliver more precise content. When you find an article of interest here, please look for the full and extensive coverage of this topic in traditional news sources, as they are written by professional journalists that we try to support, not replace. We appreciate your understanding and assistance.
Newsletter

Related Articles

0:00
0:00
Close
16 Billion Login Credentials Leaked in Unprecedented Cybersecurity Breach
Senate hearing on who was 'really running' Biden White House kicks off
Hungary Ranked Among the World’s Safest Travel Destinations for 2025
G7 Leaders Fail to Reach Consensus on Key Global Issues
FBI and Senate Investigate Allegations of Chinese Plot to Influence the 2020 Election in Biden’s Favor Using Fake U.S. Driver’s Licenses
Trump Demands Iran's Unconditional Surrender Amid Escalating Conflict
Shock Within Iran’s Leadership: Khamenei’s Failed Plan to Launch 1,000 Missiles Against Israel
Wreck of $17 Billion San José Galleon Identified Off Colombia After 300 Years
Man Convicted of Fraud After Booking Over 120 Free Flights Posing as Flight Attendant
Iran Launches Extensive Missile Attack on Israel Following Israeli Strikes on Nuclear Sites
Beata Thunberg Rebrands as Beata Ernman Amidst Sister's Activism Controversy
Hungarian Parliament Approves Citizenship Suspension Law
Prime Minister Orbán Criticizes EU's Ukraine Accession Plans
Hungarian Delicacies Introduced to Japanese Market
Hungary's Industrial Output Rises Amid Battery Sector Slump
President Sulyok Celebrates 15 Years of Hungarian Unity Efforts
Hungary's Szeleczki Shines at World Judo Championships
Visegrád Construction Trends Diverge as Hungary Lags
Hungary Hosts National Quantum Technology Workshop
Hungarian Animation Featured at Annecy Festival
Israel Issues Ultimatum to Iran Over Potential Retaliation and Nuclear Facilities
UK and EU Reach New Economic Agreement
Coinbase CEO Warns Bitcoin Could Supplant US Dollar Amid Mounting National Debt
Trump to Iran: Make a Deal — Sign or Die
Operation "Like a Lion": Israel Strikes Iran in Unprecedented Offensive
Israel Launches 'Operation Rising Lion' Targeting Iranian Nuclear and Military Sites
UK and EU Reach Agreement on Gibraltar's Schengen Integration
Israeli Finance Minister Imposes Banking Penalties on Palestinians
U.S. Inflation Rises to 2.4% in May Amid Trade Tensions
Trump's Policies Prompt Decline in Chinese Student Enrollment in U.S.
Global Oceans Near Record Temperatures as CO₂ Levels Climb
Trump Announces U.S.-China Trade Deal Covering Rare Earths
Smuggled U.S. Fuel Funds Mexican Cartels Amid Crackdown
Austrian School Shooting Leaves Nine Dead in Graz
Bezos's Lavish Venice Wedding Sparks Local Protests
Europe Prepares for Historic Lunar Rover Landing
Italian Parents Seek Therapy Amid Lengthy School Holidays
British Fishing Vessel Seized by France Fined €30,000
Dutch Government Collapses Amid Migration Policy Dispute
UK Commits to 3.5% GDP Defence Spending Under NATO Pressure
Germany Moves to Expedite Migrant Deportations
US Urges UK to Raise Defence Spending to 5% of GDP
Israeli Forces Intercept Gaza-Bound Aid Vessel Carrying Greta Thunberg
IMF Warns of Severe Global Trade War Impacts on Emerging Markets
Low Turnout Jeopardizes Italy's Citizenship Reform Referendum
Transatlantic Interest Rate Divergence Widens as Trump Pressures Powell
EU Lawmaker Calls for Broader Exemptions in Supply Chain Legislation
France's Defense Spending Plans Threatened by High National Debt
European Small-Cap Stocks Outperform U.S. Rivals Amid Growth Revival
Switzerland Proposes $26 Billion Capital Increase for UBS
×