Budapest Post

Cum Deo pro Patria et Libertate
Budapest, Europe and world news

Japanese researchers create a 'vaccine' against getting old

Japanese researchers create a 'vaccine' against getting old

Researchers at a Tokyo university say their vaccine slowed the ageing process in mice, and could even aid the treatment of ageing-related diseases.

What if you could live forever? It's a question long pondered by fictional supervillains and Silicon Valley billionaires alike.

Now researchers in Japan say they may have taken a step toward boosting human longevity with successful trials of a vaccine against the cells that contribute to the ageing process.

In laboratory trials, a drug targeting a protein contained in senescent cells - those which have naturally stopped reproducing themselves - slowed the progression of frailty in older mice, the researchers from Tokyo's Juntendo University said.

The vaccine also successfully targeted the senescent cells in fatty tissue and blood vessels, suggesting it could have a positive impact on other medical conditions linked to ageing.

"We can expect that (the vaccine) will be applied to the treatment of arterial stiffening, diabetes and other ageing-related diseases," Juntendo professor Toru Minamino told Japan's Jiji news agency.

What is cellular senescence?


Cells become senescent when they stop duplicating themselves, often in response to naturally-occurring damage to their DNA. Cellular senescence is thought to contribute to the ageing process itself, as well as ageing-related diseases like Alzheimer's and some cancers.

"Senescent cells secrete a series of factors that disrupt the function of the tissue," Dr Salvador Macip, head of the University of Leicester's Mechanisms of Cancer and Ageing Lab, told Euronews Next.

"They 'call' cells from the immune system, in theory to be cleared by them (but that eventually fails) and create a chronic low level inflammation, mixed with fibrosis," Macip said.

Macip was part of an international team of academics from universities in the UK, Spain, Nigeria and Saudi Arabia that published research on another method of tackling senescent cells in October this year.

"The biological process of ageing is very complex, therefore it is unlikely that one single strategy will completely stop it or reverse it. However, there are probably many ways to slow it down, and clearing senescent cells seems to be one of the easiest and potentially more effective," he said.

The limit on lifespan


In laboratory tests, preventing the build-up of senescent cells extended the lifespan of mice by 15 per cent, Macip told Euronews Next. Other, similar experiments have achieved as much as a 35 per cent increase, he said.

File photo. Similar experiments have reported up to a 35 per cent increase in the longevity of mice, Macip said


But before you get too excited, it's worth bearing in mind that researchers still don't know how much a living creature's lifespan can be extended.

"This is a very interesting question, and one that we still have not agreed upon. Some believe there is a 'hard' limit for human lifespan (around 130 years is the current estimate), while others think that, on paper, immortality should be feasible," Macip said.

"It's still early to know how much life can be extended and whether there's a limit or not".

We may not have to wait too long for an answer, though.

"The field of anti-ageing research is advancing very fast. In the last decade, there have been many key discoveries," Macip said.

"The person that will take the first anti-ageing pill has probably already been born".

AI Disclaimer: An advanced artificial intelligence (AI) system generated the content of this page on its own. This innovative technology conducts extensive research from a variety of reliable sources, performs rigorous fact-checking and verification, cleans up and balances biased or manipulated content, and presents a minimal factual summary that is just enough yet essential for you to function as an informed and educated citizen. Please keep in mind, however, that this system is an evolving technology, and as a result, the article may contain accidental inaccuracies or errors. We urge you to help us improve our site by reporting any inaccuracies you find using the "Contact Us" link at the bottom of this page. Your helpful feedback helps us improve our system and deliver more precise content. When you find an article of interest here, please look for the full and extensive coverage of this topic in traditional news sources, as they are written by professional journalists that we try to support, not replace. We appreciate your understanding and assistance.
Newsletter

Related Articles

0:00
0:00
Close
Bruce Willis Relocated Due to Advanced Dementia
French and Korean Nuclear Majors Clash As EU Launches Foreign Subsidy Probe
EU Stands Firm on Digital Rules as Trump Warns of Retaliation
Getting Ready for the 3rd Time in Its History, Germany Approves Voluntary Military Service for Teenagers
Denmark Confronts U.S. Diplomat Over Covert Trump-Linked Influence in Greenland
Trump Demands RICO Charges Against George Soros and Son for Funding Violent Protests
Taylor Swift Announces Engagement to NFL Star Travis Kelce
France May Need IMF Bailout, Warns Finance Minister
After the Shock of Defeat, Iranians Yearn for Change
Ukraine Finally Allows Young Men Aged Eighteen to Twenty-Two to Leave the Country
The Porn Remains, Privacy Disappears: How Britain Broke the Internet in Ten Days
YouTube Altered Content by Artificial Intelligence – Without Permission
Ukrainian Refugee Iryna Zarutska Fled War To US, Stabbed To Death
Elon Musk Sues Apple and OpenAI Over Alleged App Store Monopoly
German Chancellor Friedrich Merz: “The Current Welfare State Can No Longer Be Financed”
HSBC Switzerland Ends Relationships with Over 1,000 Clients from Saudi Arabia, Lebanon, Qatar, and Egypt
Sharia Law Made Legally Binding in Austria Despite Warnings Over 'Incompatible' Values
Dutch Foreign Minister Resigns Amid Deadlock Over Israel Sanctions
Trump and Allies Send Messages of Support to Ukraine on Independence Day Amid Ongoing Conflict
China Reels as Telegram Chat Group Shares Hidden-Camera Footage of Women and Children
MotoGP Cameraman Narrowly Avoids Pedro Acosta Crash at Hungarian Grand Prix
Wizz Air passengers screamed as storm-battered flight diverts to Bologna
European postal services halt U.S. deliveries after Trump imposes new tariffs
Urban explorer finds abandoned luxury restaurant left to decay
Fidesz leader labels Péter Magyar a ‘bluffer’ amid escalating political spat
French rope park operator arrested for denying entry to Israeli children
Újpest thrashes Zalaegerszeg 4-1 to secure first win in five matches
Profit-margin cap costs retailers 13 billion forints a month, warns trade group
Curiosity rover finds coral-like rock on Mars hinting at watery past
U.S. green policy rollback drives investors to Europe’s sustainable finance market
Special funerals rise in Hungary: boat, aerial and forest burials gain popularity
Hungary’s Kiskunság region turning into semi-desert after extreme drought
Kopasz Bálint wins world kayak 1000 m title in Milan, making him triple world champion
Budapest’s Keleti railway station to close for four weeks for track overhaul
Balaton could be unfit for swimming by 2035 and dry by 2050, scientists warn
Leaked guidelines show Meta’s AI allowed flirty and racist interactions with children
Filming of ‘Emily in Paris’ halted after assistant director dies on set
Filipino guest workers sue after Hungary moves to deport them for pregnancy
Ukraine Declares De Facto War on Hungary and Slovakia with Terror Drone Strikes on Their Gas Lifeline
A monster hit and a billion-dollar toy empire
Animated K-pop Musical ‘KPop Demon Hunters’ Becomes Netflix’s Most-Watched Original Animated Film
Canada: Nurse Suspended and Fined 93 Thousand Dollars After Stating the World’s Most Well-Known Fact Since the Creation of Adam and Eve, That There Are Only Two Genders
Elon Musk tweeted, “Europe is dying”
Far-Right Activist Convicted of Incitement Changes Gender and Demands: "Send Me to a Women’s Prison" | The Storm in Germany
Hungary Criticizes Ukraine: "Violating Our Sovereignty"
Will this be the first country to return to negative interest rates?
U.S. Treasury Secretary Whitney Bessent Backs Stablecoins to Boost Treasury Demand
Spain to Declare Disaster Zones After Massive Wildfires
Three-Minute Battery Swap Touted as Future of EVs
Beijing Military Parade to Showcase Weapons Advances
×