Budapest Post

Cum Deo pro Patria et Libertate
Budapest, Europe and world news

Breakthrough in treating diseases linked to obesity

Breakthrough in treating diseases linked to obesity

Researchers at two local universities have developed a drug that can treat diseases related to obesity.
The new drug, ABarginase, which can treat prediabetes, type 2 diabetes and nonalcoholic fatty liver disease, recently won the grand prize at the Geneva International Exhibition of Inventions.

Researchers from Polytechnic University and the Chinese University said the drug is a "safe and long-lasting cure to multiple obesity-related diseases."

They said following an eight-week observation that body weight, fatty mass, blood glucose levels and other characteristic features of diabetes in obese mice returned to normal levels after using the drug while on a normal diet.

Alisa Shum Sau-wun, associate professor in School of Biomedical Sciences at CUHK, said: "Currently, some diabetes drugs are very ineffective, others have adverse side effects, such as increasing risk of cancer. There are also diabetes drugs that cause obesity."

And the researchers reported: "Effects were apparent after the first injection. Fatty liver could be entirely reversed after regular use of the drug."

The drug uses arginine starvation, which suppresses fat synthesis, promotes fat breakdown and sensitizes cells to insulin.

They also found there is no drug resistance in a drug that exists naturally in the human body.

Shum said patients need one injection per week for the new drug while older drugs have to be taken two to three times daily.

Thomas Leung Yun-Chung, a Lo Ka Chung Charitable Foundation professor in pharmaceutical sciences at PolyU, said most people would be able to use the drug. He added: "All the test animals got much healthier after taking our drug."

Leung said the belief is that ABarginase should be much cheaper than existing drugs.

There is no drug approved by the US Food and Drug Administration for nonalcoholic fatty liver.

Patent applications have been filed in multiple jurisdictions. Researchers are now scaling up production of ABarginase in preparation for clinical trials.
Newsletter

Related Articles

0:00
0:00
Close
Ukraine Arrests Father-Son Duo In Lockbit Cybercrime Bust
US Offers $15 Million For Info On Leaders Of Cybercrime Group Lockbit
Apple warns against drying iPhones with rice
Alexei Navalny: UK sanctions Russian prison chiefs after activist's death
German economy is in 'troubled waters' - ministry
In a recent High Court hearing, the U.S. argued that Julian Assange endangered lives by releasing classified information.
Tucker Carlson says Boris Johnson wants "a million dollars, in Bitcoin or cash, from Tucker Carlson to talk about Ukraine.
Russia is rebuilding capacity to destabilize European countries, new UK report warns
EU Commission wants anti-drone defenses at Brussels HQ
Von der Leyen’s 2nd-term pitch: More military might, less climate talk
EU Investigates TikTok for Child Safety Concerns
EU Launches Probe Into TikTok Over Child Protection Under Digital Content Law
EU and UK Announce Joint Effort on Migration
Ministers Confirm Proposal to Prohibit Mobile Phone Usage in English Schools
Avdiivka - Symbol Of Ukrainian Resistance Now In Control Of Russian Troops
"Historic Step": Zelensky Signs Security Pact With Germany
"Historic Step": Zelensky Signs Security Pact With Germany
Russian opposition leader Alexey Navalny has died at the Arctic prison colony
Tucker Carlson grocery shopping in Russia. This is so interesting.
France and Germany Struggle to Align on European Defense Strategy
‘A lot higher than we expected’: Russian arms production worries Europe’s war planners
Greece Legalizes Same-Sex Marriage and Adoption Rights
Russia "Very Close" To Creating Cancer Vaccines, Says Vladimir Putin
Hungarian Foreign Minister: Europeans will lose Europe, the Union's policy must change drastically
Microsoft says it caught hackers from China, Russia and Iran using its AI tools
US Rejects Putin's Ceasefire Offer in Ukraine
The Dangers of Wildfire Smoke and Self-Protection Strategies
A Londoner has been arrested for expressing his Christian beliefs.
Chinese Women Favor AI Boyfriends Over Humans
Greece must address role in migrant vessel disaster that killed 600: Amnesty
Google pledges 25 million euros to boost AI skills in Europe
Hungarian President Katalin Novák Steps Down Amid Pardon Controversy
Activist crashes Hillary Clinton's speech, calls her a 'war criminal.'
In El Salvador, the 'Trump of Latin America' stuns the world with a speech slamming woke policing after winning a landslide election
Trudeau reacts to Putin's mention of Canadian Parliament applauding a former Ukrainian Nazi in his interview with Tucker Carlson.
The Spanish police blocked the farmers protest. So the farmers went out and moved the police car out of the way.
Volodymyr Zelenskiy fires top Ukraine army commander
Tucker Carlson's interview with Vladimir Putin raises EU concerns
Finnish Airline, Finnair, is voluntarily weighing passengers to better estimate flight cargo weight
Russia's Economy Expands by 3.6% Due to Increased Military Spending
Ukraine MPs Vote To Permit Use Of Dead Soldiers' Sperm
German Princess Becomes First Aristocrat To Pose Naked On Playboy Cover
UK’s King Charles III diagnosed with cancer
EU's Ursula von der Leyen Confronts Farmer Protests Amid Land Policy Debates
Distinguishing Between Harmful AI Media and Positive AI-Generated Content: A Crucial Challenge for the EU
Tucker Carlson explains why he interviewed Putin
Dutch farmers are still protesting in the Netherlands against the government, following the World Economic Forum's call for 'owning nothing.'
Hungarian Prime Minister Viktor Orbán stands up for European farmers and says, 'Brussels is suffocating European farmers.
This farmer seems to understand science a bit more than the event organizer, Klaus Schwab.
French farmers are not messing around.
×